High teenage BMI increases ESRD risk

Acute kidney injury increases risk of ESRD among elderly.

Risk for ESRD among elderly patients with acute kidney injury (AKI) has not been studied in a large, representative sample. This study aimed to determine incidence rates and hazard ratios for developing ESRD in elderly individuals, with and without chronic kidney disease (CKD), who had AKI. In the 2000 5% random sample of Medicare beneficiaries, clinical conditions were identified using Medicar...

Birth order and BMI in teenage girls.

The goal of this study was to investigate the relation of birth order to relative weight and prevalence of obesity in a group of 13-15 years old girls. In 1997, 1458 girls were examined. The height and weight measured by trained staff were recorded. Family size and birth order were obtained by a questionnaire. For the purpose of the present study, 776 and 250 girls coming from two- and three-ch...

Teenage drivers: patterns of risk.

PROBLEM To determine patterns of risk among teenage drivers. METHOD Review and synthesis of the literature. RESULTS On most measures, crash rates during the teenage years are higher than at any other age, for both males and females. Risk among teenagers varies greatly by driving situation; it is particularly low in some situations (e.g., the learner period) and particularly high in others (...

Inhibition of prolyl hydroxylases increases erythropoietin production in ESRD.

The reasons for inadequate production of erythropoietin (EPO) in patients with ESRD are poorly understood. A better understanding of EPO regulation, namely oxygen-dependent hydroxylation of the hypoxia-inducible transcription factor (HIF), may enable targeted pharmacological intervention. Here, we tested the ability of fibrotic kidneys and extrarenal tissues to produce EPO. In this phase 1 stud...

Lifetime risk of ESRD: a meaningful concept?